منابع مشابه
The Nucleotides That Bind: Finding the Motif behind the Hypoxia Response.
Plants need oxygen, but they don’t always get enough of it. Under waterlogging or other hypoxic conditions, oxygen is not available to act as an electron acceptor in the oxidative phosphorylation pathway. ATP production plummets, depriving the plant of the energy it needs to survive. Fortunately,many plants have developed strategies to help them endure short bouts of hypoxia. By switching to an...
متن کاملThe Ties That Bind
Using an interdisciplinary research methodology across three archaeological and historical case studies, this article explores “family archives.” Four themes illustrate how objects held in family archives, curation practices, and intergenerational narratives reinforce a family’s sense of itself: people–object interactions, gender, socialization and identity formation, and the “life course.” The...
متن کاملIdentification and partial characterization of a domain in CFTR that may bind cyclic nucleotides directly
BACKGROUND The cystic fibrosis transmembrane conductance regulator (CFTR) is a chloride channel that is activated by cAMP-dependent phosphorylation. CFTR channel activity is also stimulated by cGMP-dependent protein kinase and protein kinase C. RESULTS Here, we show that CFTR channel activation by cGMP may also occur directly. In oocytes from one-third of Xenopus donors, the activation of CFT...
متن کاملNucleotides bind to the C-terminus of ClC-5.
Mutations in ClC-5 (chloride channel 5), a member of the ClC family of chloride ion channels and antiporters, have been linked to Dent's disease, a renal disease associated with proteinuria. Several of the disease-causing mutations are premature stop mutations which lead to truncation of the C-terminus, pointing to the functional significance of this region. The C-terminus of ClC-5, like that o...
متن کاملThe different ties that bind
The different ties that bind B efore they separate into daughter cells during mitosis, sister chroma-tids are held together by cohesin complexes. But these complexes aren't the same along the entire length of the chro-matids, according to Canudas and Smith: The version of cohesin that links sister telomeres is different from the form that fastens centromeres together (1). Cohesin consists of fo...
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ژورنال
عنوان ژورنال: Nature Structural & Molecular Biology
سال: 2021
ISSN: ['1545-9985', '2331-365X', '1545-9993', '1072-8368']
DOI: https://doi.org/10.1038/s41594-020-00552-8